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Biotics Research by Biotics Research Biotics Research - Tri-Chol - 90 Capsules CLEARANCE PRICED - from your #1 source for Nutritional Supplements
$12.11Manufacturer: Biotics ResearchPart Number: 055146027000
MSRP: $26.90
Biotics Research Tri-Chol - 90 Capsules Biotics Research Tri-Chol supplies a unique combination of botanical components with specific micronutrients, with the focus on inositol hexaniacinate, to help maintain cholesterol levels that are already within a normal range.
Risk factors in cardiovascular disease Coronary artery disease (CAD) is the leading cause of death in most industrialized nations, including the U.S. Most data regarding risks associated with cardiovascular disease in general, and CAD in particular, pertain to middle-aged men.
However, after the age of 60, CAD is the primary cause of death among women . Atherosclerosis accounts for about 50% of all female deaths, although most of these occur after the age of 70 . Primary risk factors for both genders include hyperlipidemia, hypertension, smoking, diabetes, work-related stress, age, hyperhomocysteinemia and obesity.
Recent studies indicate that physical inactivity represents an additional lifestyle risk factor that ranks as high as any other, and high alcohol consumption increases the risk of death from cardiovascular disease. Hyperlipidemia and cardiovascular disease Elevated serum cholesterol and serum LDL and depressed HDL are interrelated risk factors for CAD.
High postprandial serum triglycerides are also a risk factor, though the correlation is not as strong. Recent studies indicate these risk factors become more prominent in post-menopausal women as well. After the age of 80, elevated serum cholesterol does not seem to increase the risk of CAD for men, though it may still be a factor for elderly women.
The interrelationships among the various risk factors are complex, and in subjects with more than one factor, there is a synergistic effect among various factors. For example, hyperlipidemia increases blood pressure. The liver clears dietary cholesterol, and feedback mechanisms help regulate circulating cholesterol levels.
When the cholesterol input increases, cholesterol tends to accumulate in hepatocytes. This in turn leads to down-regulation of hepatic receptors that clear LDL cholesterol from the bloodstream. In contrast to LDL, HDL functions mainly to move excess tissue cholesterol to the liver for excretion.
Elevated serum HDL, or lowered serum cholesterol/HDL ratios correlate with decreased risk of cardiovascular disease. Cholesterol oxidation and cardiovascular disease Elevated serum cholesterol increases the probability of oxidation of LDL-cholesterol (LDL-C).
Oxidized LDL-C is cytotoxic to arterial endothelial cells. According to the oxidation hypothesis of cardio-vascular disease, partially oxidized LDL-C is selectively taken up by monocytes and macrophages that evolve into lipid-filled foam cells. Scavenger receptors on these cells absorb oxidized LDL.
Unlike the LDL receptor, the scavenger receptor is not down-regulated by high levels of cytoplasmic cholesterol, and the cells continue to accumulate oxidized LDL indefinitely. In addition, it also promotes the pr.
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• Gluten Free
: Gluten Free
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